Review of the status of foot and mouth disease and approach to control/eradication in Europe and Central Asia.

Developing Vaccines against Foot-and-Mouth Disease: a Biotechnological Approach

Foot-and-mouth disease (FMD) is a contagious viral disease of livestock with significant economic effect. It is prevalent in various regions of Asia, Africa, and South America. The causative agent of this disease is called foot-and-mouth disease virus (FMDV), which is a member of Aphthovirus genus. Vaccination is an effective technique to prevent the complications of FMD and to eradicate the di...

The outbreak of Foot-and- Mouth disease (ASIA 1 Type) in 1973 in Iran

Determinants of foot-and-mouth disease in industrial dairy farms of Qazvin province: a case-control study

Foot-and-mouth disease (FMD) is a highly contagious viral disease of ruminants, which causes fever and blisters in their mouth and feet. This study, as a case- study design, was conducted to determine the factors related to FMD occurrence in the industrial dairy farms of Qazvin Province, Iran. The case unit was referred to any industrial dairy farms that had at least one cow or calf with clinic...

Rapid and accurate diagnosis of Foot-and-mouth disease virus by Real-time PCR in field samples

During 2010-2011, Real-time PCR procedure was used to detecting FMDV RNA on 147 epithelium samples from the field. In this survey, for Real-time PCR from 3D gene segment as conserve region selected for tracking all of seven serotypes FMDV. The assay detected the viral RNA in all serotypes of FMDV. The rRT-PCR specifically detected FMD virus in sample with greater sensitivity than our convention...

Optimal Control of Hand, Foot and Mouth Disease Model using Variational Iteration Method

In this paper, the optimal control of transmission dynamics of hand, foot and mouth disease (HFMD), formulated by a compartmental deterministic SEIPR (Susceptible-Incubation (Exposed)- Infected - Post infection virus shedding - Recovered) model with vaccination and treatment as control parameters is considered. The objective function is based on the combination of minimizing the number of infec...